Press releases

With the kick-off meeting that began today and will conclude tomorrow, 27 November, NASCHA – North Adriatic Smart Communities Hydrogen Accelerator is officially launched. The new initiative aims to accelerate the development and adoption of renewable hydrogen-based technologies within the North Adriatic ecosystem. The European project, which will last 36 months, has a total value of approximately EUR 11 million, of which EUR 7.9 million are funded by the I3 – Interregional Innovation Investments Instrument. NASCHA represents the natural evolution and a major extension of the North Adriatic Hydrogen Valley (NAHV) initiative, inheriting its vision of an integrated, resilient and interregional hydrogen value chain. It further strengthens this vision through demonstration activities, scalability tools for the proposed solutions, and dedicated acceleration programmes for SMEs. The project, led by Area Science Park, brings together 20 public and private organisations from Italy (mainly Friuli Venezia Giulia), Slovenia and Croatia, representing the entire hydrogen value chain: research institutions, innovative SMEs, large companies, business support organisations, universities and local authorities. NASCHA aims to develop three Smart Communities of Practice and two pilot projects to advance solutions based on new technologies in the green hydrogen sector from Technology Readiness Level (TRL) 6 to TRL 9, making them ready for the market and for investment. In addition to developing three Smart Communities of Practice (SCP) in the cities of Celje, Ajdovščina (Slovenia) and Cres (Croatia)—aimed at demonstrating the effectiveness of green hydrogen applications respectively in in urban areas, sustainable irrigation, and transport and mobility respectively through the integration of innovators, businesses, public administrations and research centres—the project also aims to strengthen the ecosystem for hydrogen production, storage and distribution across the North Adriatic territories. NASCHA indeed integrates and shares knowledge between highly innovative regions and less developed regions in the EU hydrogen value chains, contributing to the European Green Deal, the EU Hydrogen Strategy, and broader decarbonisation goals. “NASCHA contributes to accelerating the energy transition across the North Adriatic”, explains Alberto Soraci, project coordinator. “It aims to strengthen the hydrogen ecosystem by contributing to the European Green Deal. It also reinforces cross-border cooperation and the integration of technologies into key value chains such as transport and urban areas, ensuring long-term impact and enabling the replication of best practices by other regions”. One of the most innovative elements of the initiative is the allocation of dedicated funds for businesses: NASCHA will support at least 20 SMEs through cascade funding (up to EUR 60,000 each) and advanced business acceleration and investor readiness programmes. The project will also develop a set of tools designed to facilitate the adoption of the NASCHA model in other European Hydrogen Valleys, including standardised procedures, know-how for third-party selection, and matchmaking services for investors.   Project partners: Area Science Park (coordinator), META Group, ETRA, Italian Business Angels Network Association, Občina Ajdovščina, STEMwise, META Circularity, CTS H2, Grad CRES, OTRA, RRA PORIN, SIST, ECUBES, Inkubator, PATRIA, University of Zagreb – Faculty of Electrical Engineering and Computing, Energetika, Institut Jožef Stefan, Mestna Občina Celje, INCOM. Co-financed through the I3 Instrument implemented by EISMEA.  

The World Antimicrobial Resistance Awareness Week (WAAW), promoted by the World Health Organization (WHO), will take place from 18 to 24 November under this year’s theme “Preventing Antimicrobial Resistance Together: Protecting Our Present, Securing Our Future”. The main goal is to raise global awareness of the danger of antimicrobial resistance (AMR) – a phenomenon that occurs when bacteria, viruses, fungi and parasites evolve to resist the effects of medicines, making infections increasingly difficult to treat. In the lead-up to this globally significant event – from health, scientific and social perspectives – Area Science Park organised today in Trieste, in collaboration with the University of Trieste, the International Workshop “Tackling Antimicrobial Resistance: Prevention, Monitoring and Counteraction”. The event focused on prevention, monitoring and counteraction strategies to fight antimicrobial resistance (AMR). The initiative, developed within the PRP@CERIC project and promoted under the patronage of major national and international scientific institutions – including the Ministry of University and Research (MUR), the Italian Society of Microbiology (SIM) and the University of Trieste – the initiative brought together experts from academia, clinical research and industry to discuss the latest studies and innovative solutions aimed at addressing the growing threat of drug-resistant bacteria. In recent years, scientific research has been striving to find effective answers and strategies to stop the spread of antibiotic-resistant bacteria and develop therapies capable of treating infections that no longer respond to traditional treatments. International scientific cooperation remains one of the key factors in tackling what is widely recognised as one of the greatest public health challenges of our time. During the workshop, experts emphasised that monitoring is a cornerstone of the Italian National Action Plan on Antimicrobial Resistance (PNCAR). Antimicrobial resistance is an evolutionary and global process responsible for 1.27 million direct deaths and 4.95 million total associated deaths each year – a figure that exceeds the combined totals of tuberculosis and HIV. The ESKAPE group of bacteria (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Escherichia coli), together with Mycobacterium tuberculosis and Streptococcus pneumoniae, are currently among the main culprits of the most difficult infections to treat. “The situation regarding antibiotic resistance is highly heterogeneous. In Italy, we are observing growing caution and awareness in the prescription and correct use of antimicrobials — both in human medicine and in livestock farming — but globally, management of the issue remains inconsistent,” said Federica Mantovani of Area Science Park. The World Health Organization and the European Commission have both pointed out that, despite preventive measures, there is still a serious lack of innovation in this field. Of the roughly ninety drugs currently under development, only fifteen are considered truly innovative. It is crucial to intensify research — including basic research — to develop radically new therapies and overcome antibiotic resistance, since continuing to rely on existing therapeutic models will not be sufficient”. To combat the spread of AMR, coordinated action is needed at both international and local levels, based on antibiotic stewardship programmes – promoting the rational and targeted use of antimicrobials – along with continuous epidemiological surveillance and the “One Health” approach, which recognises the interconnectedness of human, animal and environmental health. “Antimicrobial resistance is a global phenomenon that requires local action,” highlighted Stefania Stefani of the University of Catania. Its impact varies greatly, with much more severe consequences in Africa, India and the Far East, where there are critical issues in accessing care and new antibiotics. In Italy, for instance, we face high mortality rates due to multidrug-resistant Gram-negative microorganisms. It is a multifactorial problem with no borders. To address it, the One Health approach is essential, recognising that resistance arises equally in humans, animals (livestock) and the environment. We must study the problem in all these contexts, identifying hotspots for resistant microorganisms — such as wastewater treatment facilities — to understand their origins and assess future risks to human health”. A significant portion of the workshop was devoted to presenting innovative therapeutic strategies, including research on human monoclonal antibodies isolated from convalescent patients, capable of preventing and treating bacterial infections and helping to identify new antigens for vaccine development. These advances open up concrete perspectives for countering resistant pathogens and reducing the global public health burden of AMR. “Monoclonal antibodies represent a promising alternative to traditional antibiotics,” explained Claudia Sala of the Biotecnopolo Foundation of Siena, “as they can target only pathogenic bacteria with high specificity, preserving the ‘good’ microbiota that is often harmed by conventional antibiotics. Monoclonal antibodies are already approved for other diseases, such as cancer and autoimmune disorders, where their use is well established. As for antibacterial antibodies, we are still in the discovery phase — and human trials take time, as they must go through multiple stages of testing”. Another promising approach, discussed by Mariagrazia Di Luca of the University of Pisa and the ICGEB, involves the use of bacteriophages, viruses that infect and destroy bacteria, emerging as precision antimicrobials for targeted therapies — for example, in cases of chronic infections. These viruses offer a highly specific solution because they selectively attack pathogenic bacteria while preserving beneficial microbiota. Thanks to scientific advances, researchers can now engineer phage cocktails and derivatives to overcome bacterial resistance mechanisms, with encouraging results already observed against multidrug-resistant pathogens such as Pseudomonas aeruginosa and Staphylococcus aureus. Nevertheless, significant challenges remain, particularly in terms of regulatory approval and large-scale production. Fighting antimicrobial resistance requires shared commitment and strengthened international cooperation — through the promotion of responsible antibiotic use, improved hygiene and infection prevention (including vaccination), and sustained support for research into new therapies.

A joint research project carried out by the Institute of Materials Workshop of the National Research Council in Trieste (Cnr-Iom), the Universities of Trieste and Innsbruck, and Elettra Sincrotrone Trieste has synthesised a new crystalline form of diboron trioxide, entirely composed of structural units previously observed only in its vitreous form. Boron oxide is commonly used as a key component in the manufacture of highly resistant glasses such as Pyrex and in enamels: in such industrial processes, it has been demonstrated that the addition of boron oxide significantly improves the glass’s ability to withstand thermal shock and chemical reactions, making it ideal for the most demanding applications. However, the vitrification process of boron oxide is still little understood, and presents anomalies not found in other oxides, such as silica, which exist in both crystalline and amorphous form. “The key distinction between a crystal and a glass lies in the ordered arrangement of atoms in the former, which is absent in the latter,” explains Alessandro Sala, a Cnr-Iom researcher who conceived the project. “Both systems are normally made up of the same structural unit composed of a few atoms, repeated in space. In crystals this ‘building block’ repeats periodically in a geometrically ordered manner, whereas in glass it repeats in a disordered way. Boron is an exception to this rule, since its vitreous phase contains elementary units composed of a ring of three boron atoms and three oxygen atoms, which are not present in the crystal. Today, for the first time, we have succeeded in obtaining a two-dimensional crystalline phase composed exclusively of the ‘building blocks’ present in the vitreous phase”. The research was based on the use of platinum as the base material to obtain this compound and to characterise its main physical properties in detail. The scientific team was able not only to develop the “recipe” for obtaining this material, but also to study its principal physical properties in depth. Maria Peressi, Full Professor at the University of Trieste, comments: “Our numerical simulations indicate that this material, porous by construction, consists of a mesh of boron and oxygen atoms that is extremely flexible, to the point of being the most elastic monoatomic-thickness material ever reported – ten times more so than graphene! This peculiar characteristic is due to the fact that the rigid ‘building blocks’ of which it is made are linked by an oxygen atom that acts as a hinge, around which they can rotate within the plane. Experimental evidence and results from numerical simulations also indicate that this material interacts only very weakly with the platinum substrate on which it is produced, suggesting the possibility of using conventional methods to separate it in order to employ it in innovative devices”. The crystalline structure of the two-dimensional material obtained was then analysed through scanning tunnelling microscopy: “The complementary measurements carried out in Trieste and Innsbruck enabled us to observe the material down to its most fundamental components,” continues Laerte Patera, Professor at the University of Innsbruck. “With the spatial resolution achieved, we are now able to determine the position of each atom within the two-dimensional mesh: in the future we will be able to observe how the atoms rearrange as the material passes from the crystalline form to the disordered form characteristic of glass”. Andrea Locatelli, head of the Nanospectroscopy beamline at Elettra Sincrotrone Trieste, concludes: “The use of synchrotron light was crucial to precisely determine the relative abundance of the constituent elements, the absence of contaminants, and the crystallinity of the new material produced. We are already capable of producing homogeneous crystals of this material measuring tens of square microns. The complementarity of the experimental techniques and theoretical simulations employed in this study proved decisive for the success of the entire scientific project. The distinctive characteristics of this new material – a wide band-gap semiconductor, extremely flexible and porous – encourage exploration of its potential use in applications across very different sectors, from electronics to catalysis to quantum technologies”. The first authors of this important work, Teresa Zio and Marco Dirindin, are two PhD students at the University of Trieste, who are brilliantly crowning a path of excellence in advanced training and introduction to research.

Imagine a universal translator that, instead of turning English into Italian, can decode the language of the proteins that make up viruses. Such a “translator” already exists: Artificial Intelligence. And it is reshaping the fight against viral diseases, from pandemic preparedness to the development of treatments. This was the key message from international experts who, today in Trieste, outlined the latest frontiers of computational virology during the workshop “AI in Virology: Leveraging AI to Advance Our Understanding of Viruses”, hosted by the Virology Unit of Area Science Park. For decades, the only way to study a virus was to grow it in the laboratory and observe its behaviour — a slow and costly process. Genetics then opened the door to reading its “instruction book”: the genome. Now AI goes further, learning the “grammar” and “syntax” of proteins — the molecular machines that allow a virus to invade cells and replicate. “New language models for proteins are like artificial brains trained on millions of biological sequences,” explains Giuditta De Lorenzo, virologist at Area Science Park. “From a single sequence of amino acids, they can identify which mutations are possible and which would instead ‘break’ the protein. This makes it possible to predict how a newly discovered virus might evolve — a crucial skill if we want to stay ahead of future pandemics. For example, our upcoming research at Area will focus on the impact of viral infection on the cell: how viruses disrupt its contents. And in collaboration with our Data Engineering Laboratory, we will also work on developing vaccines that are more effective, more stable, and designed to take into account the dynamic behaviour of viral particles   Ultra-rapid vaccines thanks to “Reverse Vaccinology 3.0” One of the most tangible impacts of AI will be on the development of vaccines and therapeutic antibodies. The so-called “Reverse Vaccinology 3.0” uses AI to instantly analyse the structure of viral proteins and identify their “Achilles’ heel” — the precise point at which antibodies can strike. “The huge advantage of Reverse Vaccinology 3.0,” explains Emanuele Andreano of the Biotecnopolo Foundation in Siena, “is the ability to discover antigens for vaccine candidates at unprecedented speed. Thanks to AI, and to advances in human immunology, it is now possible to quickly identify antibodies capable of killing a pathogen and then, from the antibody sequence, determine the target — the antigen on the surface of the virus or bacterium. This leap allows us to skip years of in vivo testing, understanding from the outset what works and what doesn’t. At the Biotecnopolo Foundation in Siena, our most important mission is to develop vaccines and monoclonal antibodies against viruses or bacteria with pandemic potential, such as the case of the monkeypox virus.” However, as noted at the workshop, this immense computing power comes with very high costs. Behind these breakthroughs are supercomputers that consume enormous amounts of energy. The public must be aware that AI, while extremely powerful, is also very expensive and demands significant investment in infrastructure.   A promising future, but one to be governed with caution The ability to read, interpret, and even “imagine” new proteins is not just an opportunity but also a profound responsibility, experts warned. “We must create shared international rules and robust control frameworks to ensure that this extraordinary scientific revolution is used solely for the benefit of humanity,” stresses Alessandro Marcello, virologist at ICGEB. “We have to consider the dual-use potential of AI, which can be very beneficial for medicine and public health, but could also pose risks if it fell into the wrong hands, given how relatively easy it could become to obtain protocols for producing highly pathogenic viruses. We must act synergistically on multiple levels: among AI developers, within the scientific community, and at the legislative level, to establish laws and regulations that, while not stifling research and innovation, protect society from these potential dangers”.

ScaleUp Lab, the capacity-building programme for technology startups promoted by Area Science Park, which aims to support new technology enterprises in developing solid, sustainable business models ready to engage with international investors. From 9 to 12 September 2025, the Summer School —organised as part of the IP4FVG-EDIH project—marks the first step of the programme: four days of intensive training that combine lectures, assessment activities and hands-on workshops. Key topics will range from open innovation to collaborative R&D models, from financial risk assessment to growth strategies, and from analysing to reinventing business models in highly dynamic markets. A significant moment will be the participation of Alexander Osterwalder, internationally recognised as one of the most influential experts in strategic innovation and co-author with Yves Pigneur of the Business Model Canvas. His presence will offer participants practical tools and proven methodologies to address the challenges of high-tech entrepreneurship and increase their chances of success in the global market. ScaleUp Lab is aimed at startups operating in high- and deep-tech sectors. Participants will have the opportunity not only to refine their skills, but also to embark on a path that will continue from September to December 2025. The programme will conclude in Trieste with Pitch Day, in mid-December, when startups will present their projects to investors and industry experts. The IP4FVG-EDIH project is funded by Italy’s National Recovery and Resilience Plan (PNRR) – Mission 4, Component 2 (M4C2) – Investment 2.3: “Strengthening and broadening the thematic and territorial scope of technology transfer centres for industry segments”, financed by the European Union – NextGenerationEU. The project aims to encourage the adoption of digital and green technologies by businesses and public administrations.

Ali Hassanali, a Senior Research Scientist at the Abdus Salam International Centre for Theoretical Physics (ICTP), has been awarded a Proof of Concept Grant by the European Research Council (ERC) to explore sustainable, skin-safe UV protection using molecules designed with Artificial Intelligence (AI). The project, CUSHOP (Capturing UV Sunlight Using Hydrogen-Bond Networks: Organic Sun Screens for Skin Protection), will combine generative AI and lab experiments to develop new organic molecules that absorb UVA and UVB rays – the two types of UV light responsible for skin damage. These molecules could be integrated into new sunscreen products, thus addressing rising skin-cancer rates and the growing concerns about the harmful impact of current sunscreens ingredients on marine ecosystems. The project will build on the ground-breaking knowledge and expertise recently developed by Hassanali and his group at ICTP as part of the ongoing ERC-funded, five-year project HyBOP (Hydrogen-Bond Networks as Optical Probes). In the years since its launch in 2022, the project has explored how organic molecules – particularly hydrogen-bonded systems – interact with light. The researchers’ deeper understanding of the molecular characteristics involved in UVA and UVB light absorption will be key in the search for new sun-shielding molecules. The funding will support two post-doctoral positions at ICTP and reinforce the Centre’s inhouse computer resources. The in-silico design of macromolecules using generative models will be carried out in close collaboration with AI experts from the Laboratory of Data Engineering of Area Science Park, coordinated by Alberto Cazzaniga. The group will also work in collaboration with Silvia Marchesan and her team at the University of Trieste to synthesise the AI-designed molecules and test their performance when integrated into sunscreen products. The expertise of a consultant from the skin-cosmetics industry will help explore the possible commercialisation of the result. Other institutions in the science and innovation system of the Trieste region, including SISSA, will be involved at different stages of the project. Hassanali’s CUSHOP is one of the 150 projects selected in 2025 by the ERC as part of their Proof of Concept Grants scheme, which supports ERC grantees in the early phases of the commercialisation or societal application of their pioneering research.

The European project POSIDON PCP (POlluted SIte DecontaminatiON Pre-Commercial Procurement) recently secured the prestigious second place in the “Innovation Procurement Initiative” category at the 2025 European Innovation Procurement Awards, presented by the European Commission. The POSIDON pre-commercial procurement, led by the Port System Authority of the Eastern Adriatic Sea in Trieste, represents a significant and pioneering example of public procurement with tangible impact. Area Science Park played a central role in coordinating the project and its technical-scientific activities related to the procurement procedure for developing innovative decontamination solutions for two complex industrial areas: the Noghere site in Trieste and the Zorrotzaurre peninsula in Bilbao, the latter at the heart of an ambitious urban regeneration plan designed by Zaha Hadid Architects. Acting on behalf of the Municipality of Bilbao and three other key contractors—SPAQUE (Belgium), CEA–City Council of Vitoria Gasteiz (Spain), and Baía do Tejo (Portugal)—the Port Authority of Trieste, supported by project partner and innovation procurement expert Sara Bedin, acquired innovative research and development services through a pre-commercial public procurement. The focus was on in situ soil decontamination at sites heavily contaminated by hydrocarbons and heavy metals. “POSIDON, characterised from its inception as a highly innovative project, is a concrete example of transferring research outcomes to the market with the goal of addressing real needs, such as developing and field-testing innovative technologies for the decontamination of soils in polluted industrial areas,” comments Caterina Petrillo, President of Area Science Park. “The effective collaboration among diverse stakeholders, the scouting of technological and innovative solutions in research laboratories, and the use of pre-commercial public procurement have been key ingredients in the project’s success, making it a European benchmark”. By initiating a competitive process from the earliest stages—conceptual design, initial development, through to large-scale field tests—POSIDON enabled the emergence of new in situ technologies that not only surpass the current state of the art (and have indeed been patented), but are also market-ready or prepared for wide commercial dissemination. In particular, the solutions selected for the field trial phase have demonstrated promising results. The Soil-Omic solution using BIOflushing® technology, already on the market, is an advanced protocol combining biological and physico-chemical treatments, integrating metagenomics with environmental engineering to decontaminate soils and aquifers from organic and inorganic pollutants. Developed by TESECO, BIOflushing utilises specialised hydraulic plants and systems for biostimulation, bio-amplification, and chemical washing of saturated and unsaturated soils. Results have confirmed the effectiveness of the process and dedicated plant in degrading petroleum and polycyclic aromatic hydrocarbons, as well as removing heavy metals from both saturated and unsaturated soils. Erase, developed by the consortium led by HCP ITALIA, is a modular patented solution currently in final refinement and pre-market development, which reduces organic and inorganic pollutants via electrodes and injections. POSIDON has received funding from the European Union’s Horizon 2020 research and innovation programme under Grant Agreement No. 776838. The content of this press release reflects only the authors’ view, and the European Research Executive Agency (REA) is not responsible for any use that may be made of the information contained therein.

The sixth edition of Startup Marathon is now underway and is an initiative dedicated to startups, innovative SMEs and university spin-offs, promoted by Area Science Park, UniCredit Start Lab and Fondazione Comunica. Over the years, this project has established a network of dozens of incubators, accelerators, universities and other organisations supporting business development throughout Italy, which have made it possible for more than 200 of the best startups across Italy to meet and make themselves known to leading SMEs, corporations and Italian and international investors who are partners in the event. In fact, the format requires the supporting organisations themselves to “present” their best startups, innovative SMEs or spin-offs by nominating them to participate in Startup Marathon. This approach makes it possible to bring together the most promising innovative proposals on the national scene in two distinct programmes: a startup competition and a targeted B2B matching programme. Confirmed following the first edition last year, the Open Innovation B2B programme is designed to allow the event’s partner companies to present their innovation needs, to which the startups will respond and these startups can, in turn, be directly nominated to intercept them. Those offering the most suitable solutions will have the opportunity, during the autumn, to engage in one-to-one meetings with corporations, in order to present their innovation projects directly. Registration for the contest follows a similar but separate process, detailed on the startupmarathon.it website. Once nominations close in September, a group of startups will be selected to present their video pitch to an audience of investors and entrepreneurs during the Startup Marathon Digital Day on 23 October, as part of the DIGITALmeet event. During this digital event, 10 finalists will be chosen to compete in a pitch competition on 20 November at UniCredit’s Tower Hall in Milan. The projects will be evaluated by a panel of judges comprised of representatives from Startup Marathon’s partners and a Scientific Committee of experts from the world of entrepreneurship, innovation and specialised press, chaired by Mariarosa Trolese, board member of the Italian Business Angel Network. The winning startups will be accompanied along a path focused on seeking grants and funding, as well as developing products and services capable of generating revenue and employment. The startup in first place will be offered participation in the UniCredit Start Lab acceleration programme and, along with the startups in second and third place, will be included among those pre-selected to take part in the national mission to CES in Las Vegas, the world’s most important trade show dedicated to innovation and new technologies. A special prize will be awarded to the best startup, innovative SME or spin-off with a female-majority ownership structure, which will be able to participate in the international BoostHerUp acceleration programme, organised by Area Science Park. There will also be a ranking for the organisations that support and nominate startups and they will be assigned a score based on the positioning of their companies. The top three will receive privileged access to the Executive MBA in Business Innovation offered by the MIB Trieste School of Management. This recognition will also be extended to all 10 finalist startups. “In six years, Startup Marathon has grown, while retaining its original practical spirit: today it represents a solid meeting point between those who develop technology and those seeking it to innovate. Last year’s introduction of the Open Innovation B2B path added a direct collaboration channel alongside the contest, which is already showing concrete results and confirming how the two souls of the initiative strengthen each other. The true value of this initiative lies in the consolidated network formed over the years between support organisations, startups and industrial partners: creating the conditions for the best technologies that emerged in Italy to find markets, capital and collaboration opportunities, generating impact and new growth for the local economic fabric”, says Roberto Pillon, Head of the Business Generation office at Area Science Park. “We are proud to support this year’s Startup Marathon once again, through UniCredit Start Lab, our business platform dedicated to startups and innovative SMEs, which, for over ten years, has accompanied hundreds of high-tech ventures on their growth paths. We consider Startup Marathon a valuable opportunity for promoting Italian entrepreneurial talent towards a more sustainable future. It’s a team game we strongly believe in, based on the shared goal of creating national and international connections between the best Italian tech companies and those who can turn their ideas into concrete solutions”, adds Francesca Perrone, Head of ESG & Start Lab Italy, UniCredit. “Startup Marathon continues to stand out as a reference point in the Italian innovation landscape, involving participants from various regional contexts, from the most developed to the most disadvantaged areas. The initiative fits perfectly into the national ecosystem of incubators, accelerators, technology parks and universities, with the aim of promoting the best Italian entrepreneurial ideas”, says Gianni Potti, President of Fondazione Comunica and founder of DIGITALmeet. “In a country where the presence of investors in the startup sector remains limited, events like Startup Marathon are vital for supporting projects that might otherwise struggle to develop without concrete backing. We have always committed to promoting dynamic and innovative enterprises, creating growth opportunities for businesses and jobs for young people”. Founded in 2020, Startup Marathon has, over the years, selected and rewarded innovative companies active in fields such as artificial intelligence, diagnostics, IoT and sustainability. Winners of past editions include Soundsafe Care, a spin-off of the Scuola Superiore Sant’Anna in Pisa that combines robotics and ultrasound for the non-invasive treatment of tumours; Katakem, a spin-off of the University of Catanzaro, that accelerates the development of new molecules; CAEmate, a company that developed software for the predictive maintenance of infrastructures; Aisent, which provides services based on AI, machine learning and computer vision, and M2Test, a spin-off of the University of Trieste that created an innovative diagnostic method for osteoporosis.

The Bernardo Nobile Award celebrates its 20th anniversary. Promoted by Area Science Park, it aims to promote the use of scientific and technical information contained within patent documentation as part of research and innovation pathways. With the 2025 edition, the Award is renewed, offering six prizes and addressing highly topical themes. The 20th edition of the Award, dedicated to the memory of Bernardo Nobile — founder and first head of the Area Science Park PatLib Centre — has been updated to recognise studies and methodologies for the analysis of data and information, both related to intellectual property and concerning potentially high-impact technologies. In particular, the main innovations include: studies that enhance the use of patent documentation and information, including through Artificial Intelligence (AI) analysis of data, information, and processes related to Intellectual Property (IP); studies and/or scenario analyses and/or technological foresight focusing on “deep-tech” technologies, with particular attention to their impact and/or valorisation. The initiative, organised with the involvement of the Italian Association of Patent Documentalists (AIDB), will award six cash prizes of €2,500 each to as many graduates and/or PhD holders who have been selected as winners in the following three categories: Category 1 and 2: respectively for Master’s theses and doctoral dissertations that explicitly use patents as an information source, possibly also analysing opportunities arising from the use of AI techniques in the research, processing and analysis of data and information, or in managing processes related to IP; Category 3: for Master’s theses and/or doctoral dissertations that have explored the impact and/or valorisation of “deep-tech” technologies, possibly including foresight, forecast, or anticipatory analyses in the following sectors: a. Life Sciences b. Materials Science c. Advanced Digital Technologies d. Green Energy Supply Chains The deadline for submitting applications is 30 June 2025. All details and the full call for applications are available here.

The European LIFE IN-PLAN project’s efforts to develop territorial plans integrating energy, climate, and mobility aspects are beginning to bear fruit by encouraging virtuous planning practices among municipalities aimed at achieving climate neutrality. A notable example is the municipality of San Vito al Tagliamento (PN), with which IN-PLAN is actively collaborating, supporting its team of experts alongside local officials in the integrated drafting of the Municipal General Urban Plan, the General Urban Traffic Plan, the Sustainable Energy and Climate Action Plan, the Green Masterplan, and the Plan for the Removal of Architectural Barriers. “We warmly welcomed the IN-PLAN project because, as a municipality belonging to the Sustainable Municipalities Network, we recognise the importance of integrated and systemic planning involving multiple stakeholders with diverse sensitivities and expertise. This approach ensures a comprehensive vision and coherence that can only be achieved through dialogue, comparison, and collaboration, as we have already experienced during an initial meeting with all the planners supporting us in drafting the various plans,” states Federica Del Frè, delegated councillor for the municipality of San Vito al Tagliamento. Very useful tools in this direction include the IN-PLAN Practice, the IN-PLAN Checklist, and the Guidelines for a Data Management Plan, which provide concrete support for public administrations and sector operators in implementing multilevel governance. “The IN-PLAN Practice offers a comprehensive guide with examples of good practices and a step-by-step approach to effectively integrate energy, climate, and territorial planning policies,” explains Fabrizia Salvi of Area Science Park. “The IN-PLAN Checklist provides a structured reference framework in the form of guiding questions to improve existing or developing plans by assessing the coherence of measures envisaged in various plans, as demonstrated by the ongoing work with the municipality of San Vito al Tagliamento. The checklist is designed to foster reflection on developing integrated measures that also consider the effects—both positive and negative—that these may have on sectors other than the primary focus. It can also be used in a preliminary phase of plan drafting to consider different aspects of an issue and choose to address them in a multidisciplinary way”. The importance of these tools, with a particular focus on the “data-driven” approach, alongside experiences of various local authorities, universities, and research centres, was central to the event held on 2 April 2025 in Padua, within the framework of the Forum Duezerocinquezero, in collaboration with the LIFE NECPlatform project and the Coordination of Italian Local Agenda 21. The event, attended by experts and stakeholders, was not only an opportunity to present the IN-PLAN methodologies and tools but also a chance to discuss the challenges of integrated planning within the National Coalition Group (NCG) of IN-PLAN. This national discussion platform offers various stakeholders the chance to exchange views and formulate proposals and recommendations on integrated planning to be subsequently shared with national policymakers. The group involves several entities, including Area Science Park, the Coordination of Italian Local Agenda 21, and the municipalities of Padua, Prato, and Narni. During the event, proposals for the NCG were presented, focusing on the importance of “data-driven” integrated territorial planning and addressing barriers to integrated design, data management, and governance forms. The LIFE IN-PLAN project, co-financed by the European Union, will continue its work until March 2026. There is still an opportunity for municipalities and provinces to join as pilots and receive support from Area Science Park experts in integrating plans by testing the methodology and tools developed by the project.

The aim is to strengthen the competitiveness of Italian businesses and promote the growth of a dynamic and future-oriented entrepreneurial ecosystem through the co-creation of innovative solutions developed by startups, spin-offs and innovative SMEs in response to the needs of medium and large enterprises. With this ambitious goal and as part of the activities and services of IP4FVG – EDIH, Area Science Park, in collaboration with ELIS Innovation Hub, is launching the Open Innovation@IP4FVG, programme through two calls: Call 4 Need, for medium and large enterprises, and Call 4 Solution, dedicated to startups, spin-offs and innovative SMEs. Thanks to the programme, the selected companies will work together, for 12 weeks, on the co-development of a Proof of Concept (PoC), a pilot project or prototype that makes it possible to test the innovative solutions and assess their effectiveness, applicability and scalability. Every stage of the approach will be guided and supported by experts from Area Science Park and ELIS Innovation Hub, through to final validation of the solution. Thanks to PNRR funds from the IP4FVG-EDIH project, selected medium and large enterprises will have access to subsidised funding of up to 80% to develop their PoC with a value of €40.000 each. The co-innovation approaches must focus on advanced digital technologies for optimising processes across the entire value chain, for reducing environmental impact and for cybersecurity. The programme includes a first local service event on 15 April at 3 p.m. in the Pasolini Room of the Friuli Venezia Giulia Region in Udine, during which companies and startups can join the programme, meet, delve deeper into the topic of Open Innovation and take part in networking sessions aimed at fostering long-term collaborations. The programme is part of the IP4FVG-EDIH services, an initiative funded by the National Recovery and Resilience Plan (PNRR) – Mission 4, Component 2 (M4C2) – Investment 2.3, subsidised by the European Union – Next Generation EU, which aims to encourage the adoption of digital and green technologies. More information on the areas and the approach is available at this link. To register for the presentation event on April 15 in Udine, click here.

China is the most attractive market for patents in the rare earth element (REE) recycling sector, with a significantly higher number of patent applications compared to other countries. This is what emerges from the study “Innovation in rare earths recycling: A quantitative and qualitative analysis of patent data”, which, through a meticulous analysis of patent data, offers an in-depth examination of innovation in the Rare Earth recycling sector. Rare earth elements are fundamental for the digital transition and decarbonisation and are used in key technologies such as batteries, wind turbines and electronic devices. However, their extraction has a significant environmental impact and the supply chain is highly concentrated in just a few countries, making recycling a strategic solution to ensure sustainable access to these resources, reduce dependence on imports and limit the environmental impact of mining activities. According to the study, published in Resources Policy and conducted by Area Science Park (Riccardo Priore and Marinella Favot) and the University of Milan-Bicocca (Marco Compagnoni), China remains the most dynamic market in the REE recycling sector and Chinese universities are the main players in innovation, demonstrating a strong commitment to research and development of new technologies for the recovery of these materials. However, the United States and Japan emerge as technological leaders, with patents that are more frequently mentioned and with greater international protection of their inventions, indicating more advanced and globally relevant technological innovation. Europe, on the other hand, shows signs of stagnation in both the number and quality of patents. To bridge the gap with the main players in the sector, greater support for innovation is needed through public investment, business incentives and international collaborations. Moreover, revising policies for managing waste of electric and electronic equipment (WEEE), which is rich in critical raw materials, is crucial to making the circular economy more effective, by improving waste collection, enhancing recycling facilities and incentivising the use of secondary raw materials. Riccardo Priore of the Patlib Centre, at Area Science Park, states that “This study represents an innovative type of support, through statistical analysis of patent documents, to various issues related to academic research activities. The study of innovation dynamics in the rare earth recycling sector provides an important starting point for developing more effective strategies in the REE recycling sector, with significant implications for the strategic autonomy of importing countries and for the future of the global circular economy.” In a context of increasing demand for rare earth elements, recycling capacity will become increasingly crucial in reducing dependence on imports and mitigating the environmental impact of extraction. The results of the study suggest that, in order to remain competitive, Western countries should intensify their efforts in the recycling sector by promoting high-quality innovations and investing in the transition to a more sustainable economy. Link to the paper