INGenIO: 21 million euros for the study of rare diseases
The INGenIO project submitted by Area Science Park under the competitive call of the National Programme for Research, Innovation and Competitiveness 2021–2027 of the Ministry of University and Research (MUR) has secured funding of over €21 million. The funding will support the development of an integrated, interoperable and distributed infrastructure for the diagnosis, molecular understanding and identification of personalised therapies for rare diseases—conditions that affect around 30 million people in Europe alone. The project ranked fifth in the merit list, with a score of 96/100.
INGenIO (Next-Generation Digital Infrastructure for the Study of Rare Diseases: Target Identification Guided by Multi-Omics & A.I. for Precision Drug Discovery & Delivery) aims to analyse clinical data from patients with rare diseases using Artificial Intelligence techniques designed to enable early diagnosis and identify potential drugs. On the experimental side, the project integrates Area Science Park’s multi-omics and digital technologies with magnetic resonance methods, electron microscopy and advanced preparative techniques available at partner laboratories. By bringing together specialised expertise and equipment across the national territory, the project will cover the entire value chain—from disease study to computational modelling and the synthesis of new drug candidates.
INGenIO, coordinated by Area Science Park, builds on the organisation’s experience in designing and implementing research infrastructures focused on life sciences, including the Pathogen Readiness Platform for the CERIC-ERIC Upgrade (PRP@CERIC) for the study of pathogens and the ORFEO data centre. The project relies on a strong partnership including the University of Salerno, the University of Salento, the University of Florence, the CNR – Institute of Materials (IOM), the University of Naples “Federico II”, which brings collaboration with TIGEM, the CERM Magnetic Resonance Centre in Florence, and ENEA in Casaccia. This is complemented by a network of companies—particularly SMEs in Southern Italy—that have already expressed interest in collaborating on the project. The project structure integrates the expertise needed to cover the entire translational research cycle and its links with the industrial system.
A distinctive feature of INGenIO, which expands the offering of the European infrastructure CERIC, is the functional integration of specialised laboratories distributed across the country and belonging to two other European research infrastructures, INSTRUCT and METROFOOD. In this way, a portfolio of instruments and expertise unique in Europe is oriented towards achieving a shared scientific objective—ambitious and with a high impact on health and society.
“INGenIO’s 100% funding and its high ranking in the national list represent an important achievement for the organisation, which in recent years has focused its activities and investments on developing research infrastructures open to both the scientific community and industry,” said Area Science Park President Prof. Caterina Petrillo. “In particular, the project is an important booster to strengthen and relaunch the development strategies of the Area Sud site in Salerno, where, together with the university, we work on multi-omics characterisation in close synergy with our laboratories in Trieste”.