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Area Science Park has significantly upgraded the hardware infrastructure and computing power of ORFEO, the Data Center that serves as a cornerstone of the organisation’s research and innovation ecosystem. Supported by the PNRR – Mission 4 “Education and Research”, the Data Center expansion marks a major step forward in computing performance and in the delivery of advanced storage and data management services for scientific applications in numerical simulation and artificial intelligence.   A more powerful and sustainable Data Center The €3 million investment through PNRR funds has enabled the creation of a new 125 kW server room equipped with high-efficiency cooling systems, reducing both the carbon footprint and operational costs. Computing capacity has been enhanced with new servers for simulations and predictive modelling, supported by three AI nodes, each with eight state-of-the-art GPU accelerators. These resources make it possible to train large language models, run computer vision applications, and analyse complex datasets in a fraction of the time. Internal interconnections have been upgraded with ultra-low-latency, high-speed links to ensure smooth data flow even under heavy workloads. Storage capacity has been increased by several petabytes, with the addition of an ultra-fast solid-state memory layer for “hot” datasets, further improving performance and efficiency. “ORFEO represents a strategic investment for Area Science Park, enabling the full operation of the organisation’s research and technological infrastructures,” explained President Caterina Petrillo. “It manages the entire data lifecycle from our genomics and virology research laboratories, materials microscopy, and soon, from the green energy production demonstrator. ORFEO also provides AI and HPC access and services to companies, driving digital transformation and business competitiveness in coordination with the regional data center network. To sustain excellence and the quality of our data science investments, Area Science Park has developed an advanced training programme for young researchers and technologists”.   A key infrastructure for scientific research As the digital core of Area Science Park’s research activities, ORFEO supports advanced projects in artificial intelligence, materials science, computational biology, and genomics. Thanks to its high-performance architecture, the Data Center enables researchers to run complex simulations, train large-scale machine learning models, and analyse massive amounts of scientific data in a reproducible and traceable way. The infrastructure also powers a broad research ecosystem focused on AI model interpretability and the energy sustainability of computational processes. ORFEO hosts automated pipelines integrating high-performance and cloud computing, ensuring data interoperability and faster analysis. Its evolution strengthens collaborations with universities, research institutions, and national and European infrastructures, consolidating Area Science Park’s role as a hub for computational research and digital innovation.   An ally for digital business transformation Beyond supporting scientific research, ORFEO is a strategic asset for enterprises seeking to innovate through high-performance computing and artificial intelligence. Area Science Park provides consulting services, feasibility studies, and Proof of Concept projects to facilitate the adoption of advanced digital solutions—from numerical simulation to data science—within a secure, high-performance environment.   ORFEO is Area Science Park’s high-performance computing and artificial intelligence Data Center, designed to support scientific research and industrial innovation. Established in 2020 to serve the life sciences, it now functions as a cross-sector platform integrating HPC, AI, and big data management. It enables the training of advanced models, digital twin simulations, and FAIR-compliant data repositories linked to the organisation’s experimental laboratories. The infrastructure provides services in Infrastructure, Platform, and Software as a Service (IaaS, PaaS, and SaaS) modes, with ready-to-use environments and tools for data science and HPC. The cluster delivers millions of computing hours annually, is connected to national research backbones (LightNet, GARR), and follows open standards to ensure interoperability and security. Technical management is entrusted to the Data Engineering Laboratory (LADE), which brings together expertise in AI, data engineering, and high-performance computing.

A joint research project carried out by the Institute of Materials Workshop of the National Research Council in Trieste (Cnr-Iom), the Universities of Trieste and Innsbruck, and Elettra Sincrotrone Trieste has synthesised a new crystalline form of diboron trioxide, entirely composed of structural units previously observed only in its vitreous form. Boron oxide is commonly used as a key component in the manufacture of highly resistant glasses such as Pyrex and in enamels: in such industrial processes, it has been demonstrated that the addition of boron oxide significantly improves the glass’s ability to withstand thermal shock and chemical reactions, making it ideal for the most demanding applications. However, the vitrification process of boron oxide is still little understood, and presents anomalies not found in other oxides, such as silica, which exist in both crystalline and amorphous form. “The key distinction between a crystal and a glass lies in the ordered arrangement of atoms in the former, which is absent in the latter,” explains Alessandro Sala, a Cnr-Iom researcher who conceived the project. “Both systems are normally made up of the same structural unit composed of a few atoms, repeated in space. In crystals this ‘building block’ repeats periodically in a geometrically ordered manner, whereas in glass it repeats in a disordered way. Boron is an exception to this rule, since its vitreous phase contains elementary units composed of a ring of three boron atoms and three oxygen atoms, which are not present in the crystal. Today, for the first time, we have succeeded in obtaining a two-dimensional crystalline phase composed exclusively of the ‘building blocks’ present in the vitreous phase”. The research was based on the use of platinum as the base material to obtain this compound and to characterise its main physical properties in detail. The scientific team was able not only to develop the “recipe” for obtaining this material, but also to study its principal physical properties in depth. Maria Peressi, Full Professor at the University of Trieste, comments: “Our numerical simulations indicate that this material, porous by construction, consists of a mesh of boron and oxygen atoms that is extremely flexible, to the point of being the most elastic monoatomic-thickness material ever reported – ten times more so than graphene! This peculiar characteristic is due to the fact that the rigid ‘building blocks’ of which it is made are linked by an oxygen atom that acts as a hinge, around which they can rotate within the plane. Experimental evidence and results from numerical simulations also indicate that this material interacts only very weakly with the platinum substrate on which it is produced, suggesting the possibility of using conventional methods to separate it in order to employ it in innovative devices”. The crystalline structure of the two-dimensional material obtained was then analysed through scanning tunnelling microscopy: “The complementary measurements carried out in Trieste and Innsbruck enabled us to observe the material down to its most fundamental components,” continues Laerte Patera, Professor at the University of Innsbruck. “With the spatial resolution achieved, we are now able to determine the position of each atom within the two-dimensional mesh: in the future we will be able to observe how the atoms rearrange as the material passes from the crystalline form to the disordered form characteristic of glass”. Andrea Locatelli, head of the Nanospectroscopy beamline at Elettra Sincrotrone Trieste, concludes: “The use of synchrotron light was crucial to precisely determine the relative abundance of the constituent elements, the absence of contaminants, and the crystallinity of the new material produced. We are already capable of producing homogeneous crystals of this material measuring tens of square microns. The complementarity of the experimental techniques and theoretical simulations employed in this study proved decisive for the success of the entire scientific project. The distinctive characteristics of this new material – a wide band-gap semiconductor, extremely flexible and porous – encourage exploration of its potential use in applications across very different sectors, from electronics to catalysis to quantum technologies”. The first authors of this important work, Teresa Zio and Marco Dirindin, are two PhD students at the University of Trieste, who are brilliantly crowning a path of excellence in advanced training and introduction to research.

Area Science Park with the Council of Presidents shares the feelings of horror, grief, indignation, and anguish over the dramatic humanitarian crisis suffered by the Palestinian population as a result of the military actions undertaken by the Israeli Government in the territory of the Gaza Strip. The brutal terrorist attack carried out by Hamas on October 7, 2023, can in no way justify what is being inflicted upon Palestinian civilians, who are victims of continuous attacks, bombings, and famine. It condemns the actions that have caused and continue to cause thousands of civilian deaths, including a very large number of children. It also condemns the obstruction of humanitarian aid access, in blatant violation of international humanitarian law, and the destruction of essential civilian infrastructure. This tragedy has led the International Court of Justice to declare the risk of a violation of the Genocide Convention, a conclusion confirmed by a special United Nations commission, which stated that Israel’s conduct of war in Gaza “bears the characteristics of genocide.” It recalls that the fundamental principles enshrined in the Italian Constitution and in international law require respect for human rights, the rejection of war, and the promotion of peace and cooperation among peoples. It reaffirms the steadfast commitment of the scientific research community to peace, as expressed in recent weeks by the staff of Public Research Institutions and Universities, as well as by various scientific and academic institutions. We endorse the words of the appeal issued by the National Academy of the Lincei, calling to “recognize the non-negotiable sacredness of the lives of children, women, and men, even in the Gaza Strip.” It expresses appreciation for the positions taken by the Israeli Academy of Sciences and Humanities and by the rectors of the main Israeli universities, who have called on the Israeli Government to undertake clear and decisive initiatives to preserve human lives in the Gaza Strip. It affirms that dialogue and diplomacy are the means for resolving conflicts and emphasizes the importance of the role of scientific and cultural diplomacy as tools for building international cooperation in favor of peace. Area Science Park therefore commits itself to promoting and strengthening specific support measures for students and researchers from Palestine, as well as from other areas affected by conflicts; to encouraging initiatives of scientific and educational cooperation with institutions from all countries in order to contribute to the affirmation and strengthening of a culture of peace, dialogue, and inclusion; to reaffirming the role of the scientific community as dedicated not only to the advancement of knowledge but also to the protection of fundamental rights and the building of conditions for peaceful coexistence among individuals and peoples; and to upholding the very nature and foundation of science as a space of cooperation, dialogue, and peaceful and collaborative exchange among individuals and peoples, beyond any border, diversity, or conflict.

The second edition of the Master in Data Management and Curation (MDMC), organised by Area Science Park and SISSA – International School for Advanced Studies, started on 22 September. This post-graduate advanced training course provides young researchers as well as professionals with advanced skills in managing research data according to the FAIR principles (Findable, Accessible, Interoperable, Reusable). This approach has become essential to ensure the quality, integrity and reusability of scientific data and to promote a culture of open science at the international level. The programme was recently presented at CERN by Mariarita de Luca and Federica Bazzocchi from Area Science Park during the Open Science Fair 2025, held in Geneva from 15 to 17 September. On that occasion, the theme of FAIR data and the advanced skills required for their management was discussed as a key element in supporting the next generation of researchers. “Today data drive discovery, innovation and decision-making,” explain the researchers from Area Science Park. “For this reason, the ability to manage and curate them responsibly is crucial. Ours is a pioneering training programme that embraces the ‘FAIR-by-design’ paradigm, going beyond theory: instead of retrofitting datasets to FAIR criteria, MDMC students learn to integrate the FAIR principles from the earliest stages of data planning within the broader context of Open Science. This innovative approach is made possible thanks to the strong collaboration between Area Science Park and SISSA, which provides a dynamic ecosystem of research and innovation”. The second edition of the Master brings together 15 students from 7 different countries, with academic backgrounds ranging from Genetics to Electronics, Physics to Data Science, as well as Linguistics, Psychology, Economics and Mathematics. The 2025–2026 class also stands out for its diverse backgrounds: 3 students already hold a PhD, 7 have a Master’s degree and 5 a Bachelor’s degree. The programme lasts ten months and combines lectures, laboratory activities and internship periods at research centres and high-tech companies. Its aim is to train professionals capable of working as Data Stewards, Data Curators, Data Engineers and Data Managers in both scientific and industrial contexts. More specifically, the structure of the course includes eight intensive weeks of in-person lectures and hands-on exercises, followed by six months of internship in cutting-edge research laboratories or data-intensive institutions. During this period, students implement FAIR-by-design workflows and pipelines in real scientific contexts. This model provides a unique opportunity to work closely with researchers, develop tailored data management strategies and face the practical challenges of semantic interoperability, metadata standards and sustainable infrastructures. By training versatile, practice-oriented data professionals, the MDMC contributes to shaping a new generation of researchers capable of transforming data from a mere research product into a strategic asset, crucial for both academic excellence and data-driven innovation. For further details, see the course’s scientific programme. Watch the video featuring testimonials from students of the first 2024–25 edition.

From September 7 to 12, 2025, Portorož hosted the 17th Multinational Congress on Microscopy (17MCM), a key meeting point for scientists and industry experts. Held biennially, the event serves as a showcase of excellence for the latest breakthroughs achieved through advanced microscopy techniques, while also highlighting the newest theoretical and instrumental innovations.  Within the special session “IMPRESS: Shaping the Future of Interoperable TEM”, which gathered 80 experts, Regina Ciancio, IMPRESS Project Coordinator at Area Science Park, outlined the main objective of the initiative: to develop an interoperable and standardized platform for transmission electron microscopy (TEM), with the potential to transform the field.  IMPRESS aims to create modular components designed with open and standardized interfaces, a promising pathway to revolutionize the way electron microscopy is conceived and used. These prototypes, developed in close collaboration with SMEs in the sector and the scientific community, are designed to be adaptable to different instruments, ensuring maximum flexibility for diverse research needs.  “This is how we can innovate in the field of TEM: by promoting interoperability by design, flexibility in practice, and co-development that turns ideas into concrete solutions, addressing the needs of different communities,” emphasized Regina Ciancio during her talk. “Everything we develop is born open and is enriched through user contributions.”  The discussion clearly underscored the need to strengthen the link between electron microscopy and the broader scientific ecosystem. The creation of shared standards, the dissemination of open knowledge, and the joint involvement of SMEs and researchers are key levers to ensure that projects like IMPRESS can change not only how instruments are designed and used, but also how collaboration between scientific and industrial communities takes shape.  In the exhibition area, Area Science Park also presented a poster on the RIANA project, which aims to provide academic and industrial researchers with transnational, integrated access to a strategic set of European research infrastructures, fostering the development of multidisciplinary projects in the field of nanoscience and nanotechnology.

The first edition of the ScaleUp Lab Summer School, an initiative promoted by Area Science Park to support innovative startups in their growth journey and developed within the IP4FVG-EDIH project, has officially come to a close. The Summer School, dedicated to startups in the digital and deep-tech sectors, was created to help newly established companies define their business development strategies, with a particular focus on growth, scalability and resilience. The programme, which involves startups from all over Italy, is structured in three stages. The first stage, which has just concluded today in Trieste, consisted of a one-week residential Summer School. The programme combined contributions from Area Science Park experts with talks delivered by internationally renowned speakers, including: Alexander Osterwalder, CEO of Strategyzer and co-creator (together with Yves Pigneur) of the Business Model Canvas, recognised as one of the most influential management tools worldwide; Alberto Di Minin, Professor of Management at the Sant’Anna School of Advanced Studies in Pisa; and Alvise Bonivento, Director of the venture capital fund Indaco Venture Partners. The second stage will involve business development experts from Area Science Park acting as coaches for the startups, providing an additional three-month field validation focused on testing and iterating their business models. This work is designed to guide the startups towards the third stage: a Pitch Day attended by leading Italian investment funds, where startups will have the opportunity to engage directly with market players and test the soundness of their ideas. “The Summer School is a high value-added activity for Area Science Park,” emphasised President Caterina Petrillo, “as it forms part of an ongoing process of continuously updating models and strategies for innovation in support of enterprise generation—fields in which our organisation has a long and consolidated track record. This programme, truly unique in its kind, combines theoretical and practical training and provides participating startups with direct access to tools and specialised knowledge thanks to interaction and dialogue with international experts.” “Without a working business model, even the best technology will not reach the market and certainly will not scale,” explained Alexander Osterwalder. “The first business model you come up with will probably be wrong, which is why you need to test it and put it under constant trial and scrutiny. Without the right tools, this is very difficult. That’s where the Business Model Canvas comes in: a very simple visual tool to map out and bring to light the logic of your company’s business, making ideas very concrete and visible so they can be shared with investors and team members. The Business Model Canvas is a universal tool, and I believe that in the technological and deep-tech fields in particular, its use is even more important.” “To prepare for investors, there are two fundamental things,” stressed Alvise Bonivento: “having a very clear idea of your business—not only your technology but also your go-to-market strategy—and learning to understand the investor: knowing who they are, what their needs are, and how they can support you. Every venture capitalist always looks at three things: competitive and technological advantage, the presence of an outstanding team—both technically and managerially—and the existence of a market ready to absorb that new technology or innovation.” “Deep-tech companies need to work with players who believe in integrating their technologies with those of others,” recommended Alberto Di Minin, “in order to align business models and jointly develop an open innovation strategy. Open innovation is crucial for a deep-tech startup for one very simple reason: it is needed to complete an innovation pathway that is also being developed within other companies.” Concluding this first step of the ScaleUp Lab pathway, Roberto Pillon, Head of the Enterprise Generation Office at Area Science Park, remarked: “We created ScaleUp Lab in full awareness of the importance of working on developing the skills of new innovative companies, which need to grow and equip themselves with all the necessary tools to face the market and bring innovation to life. After the Summer School, the programme will continue over the next three months, providing startups with support, coaching and mentoring in developing their business projects, and culminating in a Pitch Day event with a group of investors.” The IP4FVG-EDIH project is financed under Italy’s National Recovery and Resilience Plan (PNRR) – Mission 4, Component 2 (M4C2), Investment 2.3 – “Strengthening and expanding the thematic and territorial scope of technology transfer centres for industrial segments.” It is funded by the European Union’s Next Generation EU programme, with the goal of fostering the adoption of digital and green technologies by businesses and public administrations.

Imagine a universal translator that, instead of turning English into Italian, can decode the language of the proteins that make up viruses. Such a “translator” already exists: Artificial Intelligence. And it is reshaping the fight against viral diseases, from pandemic preparedness to the development of treatments. This was the key message from international experts who, today in Trieste, outlined the latest frontiers of computational virology during the workshop “AI in Virology: Leveraging AI to Advance Our Understanding of Viruses”, hosted by the Virology Unit of Area Science Park. For decades, the only way to study a virus was to grow it in the laboratory and observe its behaviour — a slow and costly process. Genetics then opened the door to reading its “instruction book”: the genome. Now AI goes further, learning the “grammar” and “syntax” of proteins — the molecular machines that allow a virus to invade cells and replicate. “New language models for proteins are like artificial brains trained on millions of biological sequences,” explains Giuditta De Lorenzo, virologist at Area Science Park. “From a single sequence of amino acids, they can identify which mutations are possible and which would instead ‘break’ the protein. This makes it possible to predict how a newly discovered virus might evolve — a crucial skill if we want to stay ahead of future pandemics. For example, our upcoming research at Area will focus on the impact of viral infection on the cell: how viruses disrupt its contents. And in collaboration with our Data Engineering Laboratory, we will also work on developing vaccines that are more effective, more stable, and designed to take into account the dynamic behaviour of viral particles   Ultra-rapid vaccines thanks to “Reverse Vaccinology 3.0” One of the most tangible impacts of AI will be on the development of vaccines and therapeutic antibodies. The so-called “Reverse Vaccinology 3.0” uses AI to instantly analyse the structure of viral proteins and identify their “Achilles’ heel” — the precise point at which antibodies can strike. “The huge advantage of Reverse Vaccinology 3.0,” explains Emanuele Andreano of the Biotecnopolo Foundation in Siena, “is the ability to discover antigens for vaccine candidates at unprecedented speed. Thanks to AI, and to advances in human immunology, it is now possible to quickly identify antibodies capable of killing a pathogen and then, from the antibody sequence, determine the target — the antigen on the surface of the virus or bacterium. This leap allows us to skip years of in vivo testing, understanding from the outset what works and what doesn’t. At the Biotecnopolo Foundation in Siena, our most important mission is to develop vaccines and monoclonal antibodies against viruses or bacteria with pandemic potential, such as the case of the monkeypox virus.” However, as noted at the workshop, this immense computing power comes with very high costs. Behind these breakthroughs are supercomputers that consume enormous amounts of energy. The public must be aware that AI, while extremely powerful, is also very expensive and demands significant investment in infrastructure.   A promising future, but one to be governed with caution The ability to read, interpret, and even “imagine” new proteins is not just an opportunity but also a profound responsibility, experts warned. “We must create shared international rules and robust control frameworks to ensure that this extraordinary scientific revolution is used solely for the benefit of humanity,” stresses Alessandro Marcello, virologist at ICGEB. “We have to consider the dual-use potential of AI, which can be very beneficial for medicine and public health, but could also pose risks if it fell into the wrong hands, given how relatively easy it could become to obtain protocols for producing highly pathogenic viruses. We must act synergistically on multiple levels: among AI developers, within the scientific community, and at the legislative level, to establish laws and regulations that, while not stifling research and innovation, protect society from these potential dangers”.

ScaleUp Lab, the capacity-building programme for technology startups promoted by Area Science Park, which aims to support new technology enterprises in developing solid, sustainable business models ready to engage with international investors. From 9 to 12 September 2025, the Summer School —organised as part of the IP4FVG-EDIH project—marks the first step of the programme: four days of intensive training that combine lectures, assessment activities and hands-on workshops. Key topics will range from open innovation to collaborative R&D models, from financial risk assessment to growth strategies, and from analysing to reinventing business models in highly dynamic markets. A significant moment will be the participation of Alexander Osterwalder, internationally recognised as one of the most influential experts in strategic innovation and co-author with Yves Pigneur of the Business Model Canvas. His presence will offer participants practical tools and proven methodologies to address the challenges of high-tech entrepreneurship and increase their chances of success in the global market. ScaleUp Lab is aimed at startups operating in high- and deep-tech sectors. Participants will have the opportunity not only to refine their skills, but also to embark on a path that will continue from September to December 2025. The programme will conclude in Trieste with Pitch Day, in mid-December, when startups will present their projects to investors and industry experts. The IP4FVG-EDIH project is funded by Italy’s National Recovery and Resilience Plan (PNRR) – Mission 4, Component 2 (M4C2) – Investment 2.3: “Strengthening and broadening the thematic and territorial scope of technology transfer centres for industry segments”, financed by the European Union – NextGenerationEU. The project aims to encourage the adoption of digital and green technologies by businesses and public administrations.

Join the first in-person edition of the IN-PLAN Train-the-Trainer programme, as part of the YES-Europe Conference!Two days of interactive training on integrated spatial planning for energy and climate, featuring real case studies, hands-on activities, and site visits. Why attend? Building on the success of previous capacity-building sessions, this edition of the Train-the-Trainer will provide participants with the knowledge, tools, and confidence to support local and regional authorities in integrating energy and climate planning into spatial planning processes. You will: Gain skills and tools to support local and regional authorities in integrated territorial planning Learn from best practices across Europe Become a certified IN-PLAN Multiplier with a Digital Badge Travel & accommodation costs covered – up to €500 for selected participants! The overall objective of IN-PLAN (Integrated Energy, Climate and Spatial Planning), of which Area Science Park is a partner, is to develop, test, and implement the IN-PLAN methodology – a long-term support structure enabling local and regional authorities to effectively implement their energy, climate, and spatial plans by integrating energy and climate planning with spatial planning. Registrations are open until 16 September 2025 (5:00 PM CET). Don’t miss the chance – join the movement for more sustainable and resilient cities! For more information and registration: IN-PLAN Train-the-Trainer Live in Vienna! – Fedarene

The study, conducted by an interdisciplinary team that included scientists from the research infrastructure consortium CERIC-ERIC, Elettra Sincrotrone Trieste, Graz University of Technology (TU Graz) and the Istituto Officina dei Materiali (IOM) of the National Research Council of Italy (IOM-CNR), has been recently published in Nature Communications. In their research, supported by CERIC-ERIC, scientists addressed a critical challenge in the field: adapting highly porous MOF materials into practical, durable, and responsive assemblies for the use in carbon capture and storage technologies, while maintaining their structural integrity and sorption capacity. Carbon neutrality goals aim to mitigate human impact on climate change achieving a balance between carbon dioxide (CO2) emissions and its adsorption or sequestration from the atmosphere. Within this context, MOFs, known for their exceptional porosity and tunable chemistry, are among the most promising candidates for future CO₂ mitigation strategies. However, their integration and use have been slowed down by difficulties in fabricating functional, stable forms—especially films or membranes—compatible with industrial systems. In this new study, researchers engineered flexible Zn-based MOF films grown as heteroepitaxial layered structures on substrates. These films incorporate functionalized organic linkers, including photo-switchable molecules like azobenzene, enabling reversible CO₂ capture triggered by light (both ultraviolet and visible). “Our findings show that it is possible to design MOF films that not only operate at near-ambient conditions but can be controlled remotely using light—an appealing strategy for smart and energy-efficient carbon capture, that enables at the same time a non-invasive control over the system,” says principal investigator author Dr Sumea Klokic, who designed the experiment and performed the related measurements in the framework of CERIC-ERIC research and is now scientist at TU Graz. By tailoring linker chemistry, the team has unlocked enhanced flexibility and responsiveness in the Zn-MOF films enabling reversible CO₂ uptake and dynamic structural adaptation at near-ambient conditions. “Using a combination of cutting-edge analytical techniques available in CERIC-ERIC Partner Facilities  — including grazing incidence wide angle X-ray scattering (GIWAXS) and infrared spectromicroscopy — we have been able to deeply characterise the reversible, low-energy system we developed, observing molecular-scale interactions and quantifying CO₂ uptake in real time —especially under external stimuli such as light and temperature.” adds Dr Giovanni Birarda, researcher at the beamline SISSI-Bio of Elettra Sincrotrone Trieste. At the SISSI beamline, infrared spectromicroscopy allows researchers to investigate the spatial distribution and molecular dynamics of CO₂ within the MOF films with high chemical specificity and micrometric resolution. Looking ahead, the researchers highlight the need for improved nanoscale imaging techniques – such as the ones that will be developed during the upcoming upgrade of Elettra Sincrotrone Trieste (Elettra 2.0), that will strive to provide complementary synchrotron methods to probe dynamic processes at even smaller length scales – to eventually map the CO₂ distribution within MOF films. Such insights could unlock further application of MOFs besides carbon storage, including gas separation devices, mixed matrix membranes, and environmental sensors.

The Science and Technology Park of Trieste continues to demonstrate its ability to attract, retain, and enhance highly qualified expertise. The latest survey on staff working at the Padriciano and Basovizza campuses of Area Science Park shows a slight increase in employment, with 2,828 personnel (as of December 31, 2024, +28 compared to the previous year). However, the most significant aspect remains the high level of education and specialization among those working in the companies and research centers based there: three-quarters hold either a university degree (48.6%) or a PhD (28.7%). The most represented disciplines are technical and scientific fields, particularly Engineering, Biotechnology, and Computer Science, in line with the Park’s areas of specialization. The annual survey conducted by the Park Development Office involved 50 companies and 8 research centers/institutions, including Area Science Park, which combines scientific activity with the management of the Park itself. Women currently represent 37% of the total workforce, amounting to 1,051 individuals, marking a slight but steady increase compared to the previous two years. The data also show that over half of the personnel—1,667 individuals—are employees, confirming the prevailing contractual stability within the system. The overall picture is completed by 844 external personnel, 234 research fellows, and 73 collaborators, reflecting a complex network of expertise spanning research, training, and technology transfer. As for origin, 64% of the personnel come from Friuli Venezia Giulia, 21% from other Italian regions, and 15% from abroad. In terms of age distribution, 47% of personnel are under 40 years old (21% under 30 and 26% in the 31–40 age group), while 24% are aged 41–50 and 29% are over 51. These figures reflect a balance between experience and new talents, benefiting continuity and generational turnover—key elements for a structured and constantly evolving research and innovation system.

A new strategic Memorandum of Understanding has been signed between Area Science Park and AVITHRAPID (Antiviral Therapeutics for Rapid Response Against Pandemic Infectious Diseases consortium) marking a step forward in their capacity to prevent and respond to future infectious disease threats. The agreement formalises a shared commitment to enhance pandemic preparedness through research excellence, antiviral development, and the creation of a long-term, sustainable infrastructure dedicated to Pandemic Preparedness. At the heart of this partnership lies the ambition to promote the 100-Day Response Framework, aimed at identifying clinical candidates against emerging pathogens within 100 days and to contribute to the development of preventive approaches. This response model builds on three key pillars: the rapid characterization of pathogens, the high-throughput screening of compound libraries to explore drug repurposing opportunities, and the acceleration of translational pipelines. Area Science Park, through PRP@CERIC, the infrastructure dedicated to pathogen research, brings advanced technological platforms to the collaboration, as well as preventive approaches and innovative strategies to counter emerging viral infections. Beyond scientific cooperation, the Memorandum opens new avenues for joint funding initiatives at European level, as well as for science communication and public engagement around pandemic response and infectious disease research. These efforts aim to foster a better-informed society and a more resilient healthcare ecosystem. In an age where speed, collaboration, and knowledge-sharing are essential to global health, this new alliance follows Europe’s determination to lead not only in innovation, but also in preparedness.