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Synthetic data, digital twin modelling, diagnostic devices, and machine learning: these are some of the topics at the heart of the Trilateral Company Mission organized today by Area Science Park, a partner of the Enterprise Europe Network, together with the Jožef Stefan Institute in Ljubljana (Slovenia) and the STEP RI Technology Park in Rijeka (Croatia). A delegation of around thirty professionals from Italian, Slovenian, and Croatian companies took part in the initiative, gathering to share solutions, experiences, and expertise in the field of artificial intelligence applied to healthcare. The meeting provided an important opportunity to discuss artificial intelligence activities with applications in the health sector, as well as the High-Performance Computing (HPC) services that the Laboratory of Data Engineering of Area Science Park makes available to SMEs. There was also strong participation from companies based in the science and technology park, which took part in the pitching session aimed at fostering mutual acquaintance among participants and promoting the launch of new technical and scientific collaborations.

Applications are now open for the new edition of the Master in Data Management and Curation (MDMC), a one-year advanced programme promoted by Area Science Park and SISSA. The course is designed to train highly qualified professionals in the management, enhancement and curation of scientific data, based on a FAIR-by-design approach. Developed in collaboration between two leading institutions in the national and international scientific landscape, MDMC is open to ITS diploma holders as well as holders of Bachelor’s, Master’s or equivalent degrees. The programme provides both theoretical knowledge and practical skills in data management and curation, with a strong focus on data quality, integrity and documentation throughout the entire data lifecycle. These competencies are essential to ensure a more reliable, transparent and responsible use of Artificial Intelligence, within the broader framework of Open Science and Data Governance practices. The programme runs for approximately 10 months and is entirely delivered in English. It combines intensive in-person teaching in Trieste with a six-month internship at research laboratories and partner organisations, during which participants develop an applied project. The programme is built around the integration of data design, quality, interoperability and the responsible use of Artificial Intelligence, preparing professionals such as Data Stewards, Data Curators, Data Engineers and Research Data Managers – roles that are increasingly in demand across both academic and industrial sectors. Students will have dedicated access to the ORFEO HPC infrastructure at Area Science Park, including a dedicated virtual machine, storage space and computing resources specifically designed to support hands-on training in data management and data-intensive research. Five scholarships funded by Area Science Park, SISSA and OGS are currently available. These cover the tuition fee and provide an additional €3,000 contribution towards living expenses in Trieste during the in-person teaching period (September–December 2026). Subject to the availability of funding through agreements with external organisations – such as the Autonomous Region of Friuli Venezia Giulia, research institutions or private companies – additional financial support, scholarships and awards may be made available and will be announced on the MDMC website. Applications must be submitted via the PICA platform by 1:00 pm (CET) on 30 June 2026. Selection will be based on the evaluation of the applicant’s CV and motivation letter; a short online interview may also be required. Full details on the call, admission requirements and course structure are available in the official call.

Area Science Park welcomed 95 students and two professors from the Department of Mathematics and Physics of the Norwegian University of Science and Technology (NTNU) of Trondheim. The delegation visited the campus of Padriciano as part of a programme aimed at gaining deeper insight into the Scientific and Innovation System of Friuli Venezia Giulia. The visit follows a first experience held in March 2024, which was highly appreciated by students and professors of the Norwegian university, encouraging them to return in 2026 with an even larger delegation. During the visit, the students had the opportunity to learn more about some of the scientific and technological excellences of Area: LAME – the Laboratory of Electron Microscopy and LADE – the Laboratory of Data Engineering. Two other realities, located in the science and technology park were presented: Picosats srl, specialised in the development and design of nanosatellites for scientific and technological applications, and ICGEB – the International Centre for Genetic Engineering and Biotechnology, whose laboratories they visited. The visit ended with the presentation of the Master in Data Management and Curation (MDMC) and of the Data Center ORFEO. The visit in Area Science Park was part of a three-day stay in Trieste, during which the Norwegian delegation also had the opportunity to learn more about other institutions of excellence of the region, including SISSA, the University of Trieste (UNITS) and ICTP, demonstrating the international appeal of the region’s scientific institutions. 

On 28 February, World Rare Disease Day is celebrated worldwide, drawing attention to a major health and social challenge: today, around 300 million people globally live with a rare disease, and treatments exist for only 5% of these conditions. According to data reported by the European Commission, between 27 and 36 million patients are affected across Europe, including more than 2 million in Italy, and in 70% of cases the disease manifests during childhood. These figures highlight the need for the scientific community to strengthen its commitment to research in order to accelerate and improve the diagnostic phase, open new therapeutic perspectives and support patients along what is often a complex care pathway. This is a particularly sensitive and important research area that requires coordinated efforts and the use of tools capable of connecting highly diverse expertise and, above all, transforming heterogeneous and complex data into knowledge useful for the diagnosis and treatment of rare diseases. Area Science Park remains actively engaged in this field. Through regional and national research projects and initiatives, the organisation has long contributed to advancing scientific knowledge in the area of rare diseases. Within the activities linked to the MIRA project, funded by the Friuli Venezia Giulia Region, the Data Engineering Laboratory – LADE is currently developing a virtual assistant based on artificial intelligence technologies to improve the timeliness of diagnosis. Artificial intelligence has the potential to speed up the identification of symptoms associated with rare diseases, suggest to physicians and researchers when further diagnostic tests may be necessary, and ultimately support specialists in formulating a diagnosis. The virtual assistant – currently being tested together with the Friuli Centrale University Health Authority (ASUFC), the project’s lead partner – is being developed by the LADE laboratory in collaboration with Aindo, an innovative company based in the Area Science Park science and technology campus and specialised in the use of synthetic data that ensure both privacy protection and data reliability. More recently, the Ministry of University and Research (MUR) announced a €21 million funding allocation in support of the INGenIO project (Next-Generation Digital Infrastructure for the Study of Rare Diseases: Target Identification Driven by Multi-Omics and AI for Precision Drug Discovery and Delivery), coordinated by Area Science Park. The project aims to develop an integrated, interoperable and distributed infrastructure for the diagnosis of rare diseases, the understanding of their molecular mechanisms and the identification of personalised therapies. By bringing together specialised expertise and advanced instrumentation across the national territory, the project will cover the entire research pipeline, from disease investigation and computational modelling to the synthesis of new candidate drugs. Area Science Park’s commitment in this field builds on the organisation’s consolidated experience in designing and implementing research infrastructures, particularly in the life sciences domain. Examples include PRP@CERIC (Pathogen Readiness Platform for CERIC-ERIC Upgrade), an infrastructure dedicated to the study of pathogens, and ORFEO, the data centre that represents the digital core of Area Science Park’s research activities, supporting advanced projects every day in artificial intelligence, materials science, computational biology and genomics.  

Ultrasound technologies for non-invasive surgery and the “superfoods” of the future, innovative electromagnets, supercapacitors for electric mobility, and satellite optical communication technologies: the national research body Area Science Park announces the five startups selected as winners of the Deep Tech Revolution call, which allocates a total of €1 million in funding to innovative high-tech business projects. Each selected startup will receive €200,000 in funding, half in cash and half in high-tech services supporting research and development activities — including privileged access to Area Science Park’s advanced infrastructures and laboratories — as well as business growth support services. Deep Tech Revolution is a programme launched by Area Science Park to promote and support frontier research and deep tech innovation, with a focus on four key areas: materials science, advanced digital technologies, green energy value chains, and life sciences. The programme will provide non-repayable funding to five entrepreneurial projects selected from dozens of applications submitted from across Italy. Soundsafe Care (Pisa) develops robotic solutions that use ultrasound technologies for extracorporeal surgical procedures without incisions; Yeastime (Rome) applies ultrasound stimulation to optimise microalgae cultivation, increasing productivity and bioactive compounds for food/feed, nutraceutical and industrial biotech applications; Novac (Modena) develops a supercapacitor for automotive applications that acts as a power reserve for battery packs, integrated into vehicles within a carbon-fibre casing to optimise weight and volume; Magnetic Future (Bologna) develops a new class of high-temperature superconducting (HTS) switches designed to facilitate the adoption of superconducting electromagnets in high-impact sectors such as nuclear fusion, wind energy, space propulsion and magnetic resonance imaging (MRI); SatEnlight (Milan) proposes the use of advanced optical technologies to increase the speed, reliability and security of satellite data transmission. « The Deep Tech Revolution programme represents an ambitious challenge within Area’s strategic framework, arising from the convergence of the organisation’s long-standing experience in innovation and venture creation with recently developed scientific research capabilities,” explained Caterina Petrillo, President of Area Science Park, who added: « The initiative supports high-risk ideas and projects which, precisely because of their innovative nature, often encounter difficulties in attracting investors. In this context, the role of Area Science Park as a public research organisation can be crucial in creating the conditions for these initiatives to emerge and grow, absorbing part of the risk that the market is sometimes not yet willing to take on». The programme. The support programme will last twelve months, and its main added value is that the startups leading the funded projects will gain privileged access to Area Science Park’s technological and research infrastructures and laboratories for the first time. The offering includes laboratories for instrumental analysis, structural, cellular and molecular biology — in particular the Genomics and Epigenomics Laboratory and Elettra Sincrotrone Trieste — as well as equipment for analysing nanomaterials and innovative energy materials through the Electron Microscopy Laboratory. It also includes the High Performance Computing (HPC) infrastructure with the Data Engineering Laboratory, and the network of demonstrators of the Digital Innovation Hub. The programme will also feature international study visits, allowing participants to connect directly with leading global innovation and research ecosystems through visits to centres of excellence and meetings with experts, entrepreneurs and researchers. In addition, training and capacity-building bootcamps and networking activities will be organised through dedicated events and meetings aimed at fostering collaboration, investment opportunities and strategic growth through connections with key stakeholders. Applications. During the open call period, 187 expressions of interest were submitted by startups, university spin-offs and research groups that registered in order to apply for the call. A total of 80 projects eventually completed the application process, coming from across the country and representing almost three quarters of Italian regions (14 out of 20). Two main hubs stand out: Lazio and Friuli Venezia Giulia, both with 15 projects each. In Lazio, most projects originate from Rome (13), while in Friuli Venezia Giulia they are mainly concentrated in Trieste (8) and Udine (6). In Northern Italy, strong participation came from Emilia-Romagna (10) and Veneto (8) — driven respectively by the university hubs of Bologna (6) and Padua (5) — as well as Lombardy (6, with Milan accounting for 5) and Piedmont (4). Central Italy, beyond the Roman hub, also shows solid participation with Tuscany (8, including 6 from Pisa) and Marche (1). From Southern Italy, 11 projects were submitted, led by Apulia (5, including 4 from Bari) and Abruzzo (3), alongside Campania (2) and Sicily (1). Overall, this geographical distribution reflects a widely distributed ecosystem, combining major metropolitan hubs and regional innovation centres with medium-sized provinces, demonstrating truly widespread participation across the national territory. « We were truly impressed by the quality of the proposals submitted,” commented Pablo Garcia Tello, Head of the EU Projects and Initiatives Development Section at CERN in Geneva, who chaired the evaluation committee responsible for assessing the projects and selecting the five startups awarded the funding. « They demonstrate not only an exceptional level of scientific and technological excellence, but also a strong commitment to translating these results into tangible benefits for society. The initiative appears very solid and promises significant developments in the future». The Startups Soundsafe Care (Pisa) Project: ØSCAR 2.0 – A robotic device for non-invasive tissue mechanical ablation Soundsafe Care is an accredited spin-off of the Sant’Anna School of Advanced Studies in Pisa that integrates robotics and ultrasound technologies to redefine surgical standards. The “Zero Scar” (ØSCAR 2.0) project operates in the field of life sciences and advanced medical technologies, focusing on innovation in non-invasive surgery. The company is developing cutting-edge devices capable of performing precise extracorporeal procedures, eliminating the need for surgical incisions while protecting surrounding healthy tissue through localised robot-assisted tumour ablation. For the development of the project, the startup will use chemical and phenotypic characterisation services, the High Performance Computing (HPC) infrastructure, and digital business environment analysis services. Yeastime (Roma) Project: US4BIOMA – Ultrasounds for Bioeconomy of Microalgae Based in Rome, Yeastime develops deep-tech solutions aimed at optimising biotechnological production processes through ultrasound stimulation. The US4BIOMA project operates in the life sciences sector by implementing innovative systems for microalgae cultivation. By integrating ultrasound modules into different reactor configurations (phototrophic and heterotrophic), the startup aims to increase biomass productivity and enhance the accumulation of high-value bioactive compounds. These compounds have applications in sectors such as novel food products, animal feed, nutraceuticals and industrial biotechnology. Yeastime will access services including genomics and epigenomics analysis, structural biology, atomic force microscopy (AFM), and digital market analysis. Novac (Modena) Project: SCARF – Structural supercapacitor pack for automotive applications embedded in a reinforced carbon fibre shell Novac is an innovative startup based in Modena active in the research and development of new materials for energy storage. The “SCARF” project aims to optimise a structural supercapacitor designed to be coupled with battery packs in the automotive sector, providing an additional power reserve for vehicles. Novac’s proprietary technology enables the supercapacitor to be integrated directly into a carbon-fibre shell, exploiting vehicle volumes that are typically unused and allowing a reduction in the size of the main battery. The project aims to demonstrate the feasibility of scalable production for high-value markets. Services requested include atomic force microscopy (AFM), support in materials science and nanotechnology, and advanced technological analyses related to energy and critical raw materials. Magnetic Future (Bologna) Project: SuperSwitch – Scalable HTS Switching Devices for Efficient Superconducting Power Systems Magnetic Future is a deep-tech spin-off from Mercatorum University and the University of Bologna, established to accelerate the adoption of superconducting electromagnets in high-impact sectors such as nuclear fusion, wind energy, space propulsion and magnetic resonance imaging (MRI). The project aims to validate a new class of high-temperature superconducting (HTS) switches, essential components for flux pumps, innovative power supply systems that significantly improve the energy efficiency of superconducting magnets. The initiative lies at the frontier of applied superconductivity and power conversion technologies for the energy transition. The startup will benefit from HPC infrastructure and advanced analytical services in the fields of energy, hydrogen and critical raw materials. SatEnlight (Milano) Project: SatEnlight – Unlocking the full potential of Optical Communications SatEnlight, a Milan-based startup at the forefront of terrestrial and satellite communications, proposes the use of advanced optical technologies to increase the speed, reliability and security of data transmission. Thanks to two exclusive patents for an optical reception system based on orbital angular momentum (OAM), the company aims to transform the sector. The technology uses so-called optical vortices to multiplex multiple data channels onto a single laser beam, dramatically increasing bandwidth efficiency. SatEnlight’s mission is to establish a new standard for high-performance space communications. The development programme includes digital business analysis services and access to the High Performance Computing (HPC) infrastructure.

The Nextstep program has officially opened its second round of applications, offering 10 fully funded PhD fellowships scheduled to begin in Autumn 2026. These positions represent the first tranche of a total of 18 spots that will be made available between February and March 2026. Program Details Supported by the MSCA COFUND actions of Horizon Europe, the project aims to cultivate a new generation of researchers within a world-class international setting. Research Fields: Physics, materials science, chemistry, biochemistry, and engineering Technological Focus: Utilization of advanced neutron, X-ray, and electron microscopy techniques to address challenges in sustainability and industrial competitiveness Host Institutions: ESRF, ILL, Forschungszentrum Jülich (FZJ), and Area Science Park. In addition to working at one of these leading European research institutions, PhD candidates will benefit from enrollment in a doctoral program at a partner university and a secondment period of at least two months with academic or industrial partners. Regarding the PhD program to be developed at Area Science Park, the focus will be on the advanced study of functional materials using high-resolution Transmission Electron Microscopy (TEM) techniques, including in-situ and operando methodologies. The objective is to analyze the nanostructure of materials down to sub-Angstrom resolution, as well as to study their evolution under realistic operating conditions by applying various stimuli such as temperature, electric fields, and reactive environments (liquids or gases). The selected candidate will be enrolled in the PhD program in Nanotechnology at the University of Trieste and will conduct their research activity full-time at the Electron Microscopy Laboratory (LAME) of Area Science Park in Trieste. How to Apply: Submit your application at https://nextstep-programme.eu/job-offers/. Deadline: March 31, 2026.

The INGenIO project submitted by Area Science Park under the competitive call of the National Programme for Research, Innovation and Competitiveness 2021–2027 of the Ministry of University and Research (MUR) has secured funding of over €21 million. The funding will support the development of an integrated, interoperable and distributed infrastructure for the diagnosis, molecular understanding and identification of personalised therapies for rare diseases—conditions that affect around 30 million people in Europe alone. The project ranked fifth in the merit list, with a score of 96/100. INGenIO (Next-Generation Digital Infrastructure for the Study of Rare Diseases: Target Identification Guided by Multi-Omics & A.I. for Precision Drug Discovery & Delivery) aims to analyse clinical data from patients with rare diseases using Artificial Intelligence techniques designed to enable early diagnosis and identify potential drugs. On the experimental side, the project integrates Area Science Park’s multi-omics and digital technologies with magnetic resonance methods, electron microscopy and advanced preparative techniques available at partner laboratories. By bringing together specialised expertise and equipment across the national territory, the project will cover the entire value chain—from disease study to computational modelling and the synthesis of new drug candidates. INGenIO, coordinated by Area Science Park, builds on the organisation’s experience in designing and implementing research infrastructures focused on life sciences, including the Pathogen Readiness Platform for the CERIC-ERIC Upgrade (PRP@CERIC) for the study of pathogens and the ORFEO data centre. The project relies on a strong partnership including the University of Salerno, the University of Salento, the University of Florence, the CNR – Institute of Materials (IOM), the University of Naples “Federico II”, which brings collaboration with TIGEM, the CERM Magnetic Resonance Centre in Florence, and ENEA in Casaccia. This is complemented by a network of companies—particularly SMEs in Southern Italy—that have already expressed interest in collaborating on the project. The project structure integrates the expertise needed to cover the entire translational research cycle and its links with the industrial system. A distinctive feature of INGenIO, which expands the offering of the European infrastructure CERIC, is the functional integration of specialised laboratories distributed across the country and belonging to two other European research infrastructures, INSTRUCT and METROFOOD. In this way, a portfolio of instruments and expertise unique in Europe is oriented towards achieving a shared scientific objective—ambitious and with a high impact on health and society. “INGenIO’s 100% funding and its high ranking in the national list represent an important achievement for the organisation, which in recent years has focused its activities and investments on developing research infrastructures open to both the scientific community and industry,” said Area Science Park President Prof. Caterina Petrillo. “In particular, the project is an important booster to strengthen and relaunch the development strategies of the Area Sud site in Salerno, where, together with the university, we work on multi-omics characterisation in close synergy with our laboratories in Trieste”.