{"id":5733,"date":"2024-02-22T09:45:58","date_gmt":"2024-02-22T08:45:58","guid":{"rendered":"https:\/\/www.areasciencepark.it\/immagini-radiologiche-del-polmone-con-una-risoluzione-senza-precedenti-realizzate-a-elettra-sincrotrone\/"},"modified":"2024-07-24T16:19:20","modified_gmt":"2024-07-24T14:19:20","slug":"x-ray-images-of-the-lung-with-unprecedented-resolution-made-at-elettra-sincrotrone","status":"publish","type":"post","link":"https:\/\/www.areasciencepark.it\/en\/x-ray-images-of-the-lung-with-unprecedented-resolution-made-at-elettra-sincrotrone\/","title":{"rendered":"X-ray images of the lung with unprecedented resolution made at Elettra Sincrotrone"},"content":{"rendered":"<p>The most important European scientific journal on lung diseases, the\u00a0<em>European Respiratory Journal<\/em>, has just published the results of a\u00a0<strong><a href=\"https:\/\/erj.ersjournals.com\/content\/early\/2024\/01\/19\/13993003.01604-2023\" target=\"_blank\" rel=\"noopener\">multidisciplinary research<\/a><\/strong>\u00a0project carried out at\u00a0<strong>Elettra Sincrotrone Trieste<\/strong>, which demonstrated how, thanks to the unique characteristics of the X-rays produced by the Elettra source, it is possible to obtain a\u00a0<strong>significant improvement in X-ray images of the lung<\/strong>\u00a0compared to a CAT scan made at a hospital. The study, coordinated by Dr.\u00a0<strong>Giuliana Tromba<\/strong>\u00a0from Elettra, involved the collaboration of Prof.\u00a0<strong>Marco Confalonieri<\/strong>, Director of the Struttura Complessa Pneumologia (Complex Pneumology Structure) of the Cattinara University Hospital in Trieste, and doctors\u00a0<strong>Christian Dullin<\/strong>\u00a0and\u00a0<strong>Willi Wagner<\/strong>, researchers from the Universities of G\u00f6ttingen and Heidelberg in Germany.<\/p>\n<p>Currently, with the latest high-resolution CAT machines, it is possible to observe details of the human lung down to the limit of about 0.5 millimeters; however, extending visibility to smaller details would result in a significant increase in the radiation dose administered to the patient. At Elettra, the German-Italian research team demonstrated that,\u00a0<strong>thanks to the innovative \u2018phase contrast\u2019 technique<\/strong>, which takes advantage of the peculiar characteristics of synchrotron light (such as monochromaticity and spatial coherence),\u00a0<strong>a view of lung tissue can be obtained with effective resolutions of 0.067 millimeters<\/strong>, i.e., much higher,\u00a0<strong>with a radiation dose to the patient reduced by 2-3 times compared to CAT<\/strong>.<\/p>\n<p>Practically speaking, with this technique it is possible to produce an image of a significantly higher quality by discriminating the various anatomical components and structures much better than with a conventional CAT scan. This makes potentially very useful information available for early recognition of pathological lesions such as tumors and pulmonary fibrosis.<\/p>\n<p>The experiments at Elettra were carried out at the\u00a0<strong>SYRMEP<\/strong>\u00a0(SYnchrotone Radiation for MEdical Physics)\u00a0<strong>beamline<\/strong>\u00a0and on an animal model, i.e. pig lungs, which have the property of being the most similar to human lungs. The lungs, obtained as waste from pig slaughtering in Germany, were transferred to Italy and exposed to the Elettra synchrotron light. The newly published results have made it possible<strong>\u00a0to explore the morphology of lung tissue with an unprecedented level of resolution<\/strong>.<\/p>\n<p>With the\u00a0<strong>new Elettra 2.0 light machine currently under construction<\/strong>, which will achieve much higher X-ray energies, these studies can be extended to patients in hospitals in the Friuli Venezia Giulia region. In the examinations of patients, the new technique will allow the densitometric and structural changes caused by different pathologies to be highlighted very effectively, recognising the nature of the pathological lesion more quickly.<\/p>\n<p>According to Prof.\u00a0<strong>Marco Confalonieri<\/strong>\u00a0\u201cThe research work carried out in Trieste will soon allow us to study the human lung as if we had a huge microscope available to us, maximising resolution and mimimising the radiation dose. I am extremely satisfied that our multidisciplinary research work has received this important European recognition. It is the result of the multi-year collaboration between the School of Specialisation in Respiratory Diseases of the University of Trieste and Elettra Sincrotrone Trieste with which we have had an agreement since the opening of the School of Specialisation\u201d.<\/p>\n<p>Dr.\u00a0<strong>Giuliana Tromba<\/strong>\u00a0is also delighted with the work done and the results obtained, which have been appropriately recognised and enhanced in value by this prestigious publication: \u201cThe research team hopes to soon be able to make available to the Trieste healthcare system an innovative way of viewing the alterations created in the lung by serious diseases such as tumors and pulmonary interstitial fibrosis.\u201d The first lung CAT clinical protocol will be aimed primarily at cases where traditional diagnosis leaves interpretive doubts. These are the situations in which the potential of synchrotron light proves crucial in understanding and characterising tissue abnormalities.<\/p>\n<p>The President of Elettra Sincrotrone Trieste, Prof.\u00a0<strong>Alfonso Franciosi<\/strong>, expressed great appreciation for the research carried out, announcing that \u201cfrom 2026 onwards, when the new Elettra 2.0 light machine becomes operational, a dedicated radiology clinic will be set up on the new SYRMEP-Life Science line which will be able to accommodate patients from all over the Region and will be a unique worldwide resource for medical research\u201d.<\/p>\n<p><strong><em><a href=\"https:\/\/erj.ersjournals.com\/content\/early\/2024\/01\/19\/13993003.01604-2023\" target=\"_blank\" rel=\"noopener\">Download the research study here<\/a><\/em><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The most important European scientific journal on lung diseases, the\u00a0European Respiratory Journal, has just published the results of a\u00a0multidisciplinary research\u00a0project carried out at\u00a0Elettra Sincrotrone Trieste, which demonstrated how, thanks to the unique characteristics of the X-rays produced by the Elettra source, it is possible to obtain a\u00a0significant improvement in X-ray images of the lung\u00a0compared to [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":5862,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[313,301],"tags":[],"class_list":["post-5733","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-from-our-campuses","category-press-releases"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.9 - 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